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D.1

human nutrition

Essential Idea:  A balance diet is essential to human health.

Nature of Science:  Falsification of theories with one theory being superseded by another: scurvy was thought to be specific to humans, because attempts to induce the symptoms in laboratory rats and mice were entirely unsuccessful.

UNDERSTANDINGS:

  • 6.6.U1  Insulin and glucagon are secreted by ‘𝛃’ and ‘α’ cells in the pancreas.

  • 6.6.U2  Thyroxin is secreted by the thyroid gland to regulate metabolic rate and help control blood temperature.

  • 6.6.U3  Leptin is secreted by cells in adipose tissue and acts on the hypothalamus of the brain to inhibit appetite.

  • 6.6.U4 Melatonin is secreted by the pineal gland to control circadian rhythms.

  • 6.6.U5  A gene on the Y chromosome causes embryonic gonads to develop as testes and secrete testosterone.

  • 6.6.U6 Testosterone causes prenatal development of male genitalia and both sperm production and development of male secondary sexual characteristics during puberty.

  • 6.6.U7  Oestrogen and progesterone cause prenatal development of female reproductive organs and female secondary sexual characteristics during puberty.

  • 6.6.U8  The menstrual cycle is controlled by negative and positive feedback mechanisms involving ovarian and pituitary hormones.

APPLICATIONS & SKILLS:

  • Application:  Causes and treatment of Type I and Type II diabetes.

  • Application:  Testing of leptin on patients with clinical obesity and reasons for the failure to control the disease.

  • Application: Causes of jet lag and use of melatonin to alleviate it.

  • Application:  The use of IVF of drugs to suspend the normal secretion of hormones, followed by the use of artificial doses of hormones to induce superovulation and establish a pregnancy.

  • Application:  William Harvey’s investigation of sexual reproduction in deer.

  • Skill:  Annotate diagrams of the male and female reproductive system to show names of structures and their functions.

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